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Microwave assisted synthesis of hybrid heterocyclics

By: Srinivas, A.
Publisher: New Delhi CSIR 2021Edition: Vol.60(B), Aug.Description: 1103-1109p.Subject(s): GENERAL CHEMISTRYOnline resources: Click here In: Indian journal of chemistry (Section B)Summary: Treatment of 2-(2-((3aR,4S,6S,6aS)-6-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2,2-dimethyltetrahydrofuro [3,4-d][1,3]dioxol-4-yl)-4-oxo-3-phenylthiazolidin-5-yl)acetic acid o-phenyl diamine in conventional and microwave irradiation gives 5-((1H-benzo[d]imidazol-2-yl)methyl)-2-((3aR,4S,6S,6aS)-6-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2,2-dimethyl tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-3-phenylthiazolidin-4-one. Characterization of new compounds has been done by means of IR, NMR, MS and elemental analysis.
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Treatment of 2-(2-((3aR,4S,6S,6aS)-6-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2,2-dimethyltetrahydrofuro [3,4-d][1,3]dioxol-4-yl)-4-oxo-3-phenylthiazolidin-5-yl)acetic acid o-phenyl diamine in conventional and microwave irradiation gives 5-((1H-benzo[d]imidazol-2-yl)methyl)-2-((3aR,4S,6S,6aS)-6-((1-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)methoxy)-2,2-dimethyl tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-3-phenylthiazolidin-4-one. Characterization of new compounds has been done by means of IR, NMR, MS and elemental analysis.

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